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Article

Effect of CYP2C9-VKORC1 interaction on warfarin stable dosage and its predictive algorithm.

Journal of clinical pharmacology - 1 Mar 2015

Li Xi, Liu Rong, Yan Han, Tang Jie, Yin Ji-Ye, Mao Xiao-Yuan, Yang Fang, Luo Zhi-Yin, Tan Sheng-Lan, He Hui, Chen Xiao-Ping, Liu Zhao-Qian, Li Zhi, Zhou Hong-Hao, Zhang Wei

Abstract excerpt

This study aimed to identify the effect of CYP2C9-VKORC1 interaction on warfarin dosage requirement and its predictive algorithm by investigating four populations. Generalized linear model was used to evaluate the relationship between the interaction and warfarin stable dosage (WSD), whereas multiple linear regression analysis was applied to construct the WSD predictive algorithm. To evaluate the effect of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25187307
DOI: 10.1002/jcph.392

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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