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Article

The ERBB pathway is recurrently mutated in gallbladder carcinoma.

Cancer discovery - 1 Sept 2014

Abstract excerpt

Mutations in ERBB family receptors or downstream effectors are found in 37% of gallbladder carcinomas.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25185194
DOI: 10.1158/2159-8290.CD-RW2014-155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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The ERBB pathway is recurrently mutated in gallbladder carcinoma.PMID 25185194Read ↗

Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway.Semantic proximity Read ↗

Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention.Semantic proximity Read ↗

Identification of Altered Genes in Gallbladder Cancer as Potential Driver Mutations for Diagnostic and Prognostic Purposes: A Computational ApproachSemantic proximity Read ↗

Genomic ERBB2 / ERBB3 mutations promote PD-L1-mediated immune escape in gallbladder cancer: a whole-exome sequencing analysisSemantic proximity Read ↗

ERBB2 I655V mutation correlates with efficacy of immunotherapy in gallbladder cancer.Semantic proximity Read ↗

Somatic genetic aberrations in gallbladder cancer: comparison between Chinese and US patientsSemantic proximity Read ↗

Identification of MAP kinase pathways as therapeutic targets in gallbladder carcinoma using targeted parallel sequencing.Semantic proximity Read ↗

Oncogenes in tumors of gallbladder and biliary tract.Semantic proximity Read ↗

Genomic profiling of gallbladder carcinoma: Targetable mutations and pathways involved.Semantic proximity Read ↗

ERBB2 S310F mutation independently activates PI3K/AKT and MAPK pathways through homodimers to contribute gallbladder carcinoma growth.Semantic proximity Read ↗

Genomic and molecular landscape of gallbladder cancer elucidating pathogenic mechanisms novel therapeutic targets and clinical implications.Semantic proximity Read ↗

<i>ERBB2</i> and <i>KRAS</i> Alterations Mediate Response to EGFR Inhibitors in early stage Gallbladder CancerSemantic proximity Read ↗

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