Article
Comprehensive Molecular Characterization of Gallbladder Carcinoma and Potential Targets for Intervention.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2022
Giraldo Nicolas A, Drill Esther, Satravada Baby A, Dika Imane El, Brannon A Rose, Dermawan Josephine, Mohanty Abhinita, Ozcan Kerem, Chakravarty Debyani, Benayed Ryma, Vakiani Efsevia, Abou-Alfa Ghassan K, Kundra Ritika, Schultz Nikolaus, Li Bob T, Berger Michael F, Harding James J, Ladanyi Marc, O'Reilly Eileen M, Jarnagin William, Vanderbilt Chad, Basturk Olca, Arcila Maria E
Abstract excerpt
PURPOSE: Gallbladder carcinoma (GBC) is an uncommon and aggressive disease, which remains poorly defined at a molecular level. Here, we aimed to characterize the molecular landscape of GBC and identify markers with potential prognostic and therapeutic implications. EXPERIMENTAL DESIGN: GBC samples were analyzed using the MSK-IMPACT (Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer...
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