Article
Association of HLA-DRB1*15:02 and DRB5*01:02 allele with the susceptibility to systemic sclerosis in Thai patients.
Rheumatology international - 1 Aug 2013
Louthrenoo Worawit, Kasitanon Nuntana, Wichainun Ramjai, Wangkaew Suparaporn, Sukitawut Waraporn, Ohnogi Yuka, Nakaue Naoko, Kuwata Shoji, Takeuchi Fujio
Abstract excerpt
A genetic study, particularly in HLA-DRs, has never been performed in Thai patients with systemic sclerosis (SSc). This study was performed to investigate the association between the HLA-DR series in Thai SSc patients. HLA-DR subtypes were determined in 50 Thai SSc patients and 99 healthy controls (HCs). All SSc patients met the ACR classification criteria for SSc. HLA-DR typing was performed using INNO-LiPA...
Topics
- Adult
- Aged
- Alleles
- Asian People
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- HLA-DRB1 Chains
- HLA-DRB5 Chains
- Humans
- Male
- Middle Aged
- Scleroderma, Systemic