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Article

Mannose-binding lectin gene as a modifier of the cystic fibrosis phenotype in Argentinean pediatric patients.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Jan 2015

Gravina Luis Pablo, Crespo Carolina, Giugno Hilda, Sen Luisa, Chertkoff Lilien, Mangano Andrea, Castaños Claudio

Abstract excerpt

BACKGROUND: There is a considerable variation in the phenotype and course of the disease in cystic fibrosis (CF) even in patients with the same CFTR genotype, suggesting that other factors are important for prognosis. Mannose-binding lectin (MBL) has been proposed as one of these factors. We therefore investigated the influence of MBL2 gene variants on disease severity, age at acquisition of Pseudomonas...

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Source

Identifiers

PMID: 25178872
DOI: 10.1016/j.jcf.2014.07.012

Genes

MBL2
CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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