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Article

Deficiency of the mannan-binding lectin pathway of complement and poor outcome in cystic fibrosis: bacterial colonization may be decisive for a relationship.

Clinical and experimental immunology - 1 Feb 2005

Carlsson M, Sjöholm A G, Eriksson L, Thiel S, Jensenius J C, Segelmark M, Truedsson L

Abstract excerpt

In cystic fibrosis (CF) prognosis concerning lung damage development is highly variable and difficult to predict. Mannan-binding lectin (MBL) deficiency has been reported to be associated with poor outcome in CF lung disease. MBL is a recognition molecule of the MBL pathway of the complement system and is encoded by a gene characterized by a high degree of polymorphism. Some genotypes result in low serum...

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Source

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Identifiers

PMID: 15654829
DOI: 10.1111/j.1365-2249.2004.02690.x
PMCID: PMC1809291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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