Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Association With Pseudomonas aeruginosa Acquisition in Cystic Fibrosis: Influence of Surfactant Protein D and Mannose-Binding Lectin.

Frontiers in immunology - 1 Jan 2021

Nourkami-Tutdibi Nasenien, Freitag Klemens, Zemlin Michael, Tutdibi Erol

Abstract excerpt

Background:Pseudomonas aeruginosa (PA) infection in cystic fibrosis (CF) is associated with poor prognosis. Surfactant protein-D (SFTPD) and mannose-binding lectin (MBL) play a critical role in innate immunity and response to bacterial infections. We investigated serum levels and genetic variants of SFTPD and MBL in CF patients. Method: Thirty-five Caucasian patients homozygous for ΔF508del were genotyped for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cystic Fibrosis
Share to Follow-Up Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant

Share to Mannose-Binding Lectin

Share to Prognosis

Share to Pseudomonas aeruginosa

Share to Pseudomonas Infections

Share to Pulmonary Surfactant-Associated Protein D

Source

Open in PubMed Open full text

Identifiers

PMID: 33679736
DOI: 10.3389/fimmu.2021.587313
PMCID: PMC7933032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Association With Pseudomonas aeruginosa Acquisition in Cystic Fibrosis: Influence of Surfactant Protein D and Mannose-Binding Lectin.PMID 33679736Read ↗

Impact of mannose-binding lectin insufficiency on the course of cystic fibrosis: A review and meta-analysis.Semantic proximity Read ↗

Potential of lung surfactant proteins, SP-A and SP-D, and mannan binding lectin for therapy and genetic predisposition to allergic and invasive aspergillosis.Semantic proximity Read ↗

Polymorphisms in the lectin pathway genes as a possible cause of early chronic Pseudomonas aeruginosa colonization in cystic fibrosis patients.Semantic proximity Read ↗

Structure, genetics and function of the pulmonary associated surfactant proteins A and D: The extra-pulmonary role of these C type lectins.Semantic proximity Read ↗

The role of mannose-binding lectin in pneumococcal infection.Semantic proximity Read ↗

Serum-surfactant SP-D correlates inversely to lung function in cystic fibrosis.Semantic proximity Read ↗

Study of the effect of DNA polymorphisms in the mannose-binding lectin gene (MBL2) on disease severity in Slovak cystic fibrosis patients.Semantic proximity Read ↗

Change in Pseudomonas aeruginosa prevalence in cystic fibrosis adults over time.Semantic proximity Read ↗

Genome-wide association study of susceptibility to Pseudomonas aeruginosa infection in cystic fibrosis.Semantic proximity Read ↗

Association of polymorphisms in the mannose-binding lectin gene and pulmonary morbidity in preterm infants.Semantic proximity Read ↗

Mannose-binding lectin gene as a modifier of the cystic fibrosis phenotype in Argentinean pediatric patients.Semantic proximity Read ↗

Influence of genetic variability at the surfactant proteins A and D in community-acquired pneumonia: a prospective, observational, genetic study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.