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Article

CALR mutation screening in pediatric primary myelofibrosis.

Pediatric blood & cancer - 1 Dec 2014

An Wenbin, Wan Yang, Guo Ye, Chen Xiaojuan, Ren Yuanyuan, Zhang Jingliao, Chang Lixian, Wei Wei, Zhang Peihong, Zhu Xiaofan

Abstract excerpt

BACKGROUND: Primary myelofibrosis (PMF) is quite rare in children. Mutations of JAK2(V617F) or MPL(W515K/L) were absent in pediatric patients with PMF according to previous studies. Recently, mutations in calreticulin (CALR) were described in adult patients with JAK2/MPL-unmutated PMF. Our study...

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Source

Identifiers

PMID: 25176567
DOI: 10.1002/pbc.25211

Genes

CALR
JAK2
MPL
ASXL1
CBL
IDH1
IDH2
SRSF2
TET2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25176567-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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