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Article

Calreticulin mutation profile in Indian patients with primary myelofibrosis.

Hematology (Amsterdam, Netherlands) - 1 Dec 2015

Sazawal Sudha, Singh Neha, Mahapatra Manoranjan, Saxena Renu

Abstract excerpt

INTRODUCTION: Somatic mutations in Calreticulin (CALR) have been recently discovered in JAK2/MPL unmutated patients with primary myelofibrosis (PMF) or essential thrombocythemia. METHODS: Clinical and hematologic features were obtained for 80 patients with PMF. JAK2V617F mutation was analyzed by DNA tetra-primer amplification refractory mutation system (ARMS-PCR). CALR and MPL mutations were identified by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25959795
DOI: 10.1179/1607845415Y.0000000018

Genes

CALR
MPL
JAK2

Variants

Provenance

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