Article
PolyTB: a genomic variation map for Mycobacterium tuberculosis.
Tuberculosis (Edinburgh, Scotland) - 1 May 2014
Coll Francesc, Preston Mark, Guerra-Assunção José Afonso, Hill-Cawthorn Grant, Harris David, Perdigão João, Viveiros Miguel, Portugal Isabel, Drobniewski Francis, Gagneux Sebastien, Glynn Judith R, Pain Arnab, Parkhill Julian, McNerney Ruth, Martin Nigel, Clark Taane G
Abstract excerpt
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is the second major cause of death from an infectious disease worldwide. Recent advances in DNA sequencing are leading to the ability to generate whole genome information in clinical isolates of M. tuberculosis complex (MTBC). The identification of informative genetic variants such as phylogenetic markers and those associated with drug resistance or...
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