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Article

Two new rapid SNP-typing methods for classifying Mycobacterium tuberculosis complex into the main phylogenetic lineages.

PloS one - 1 Jan 2012

Stucki David, Malla Bijaya, Hostettler Simon, Huna Thembela, Feldmann Julia, Yeboah-Manu Dorothy, Borrell Sonia, Fenner Lukas, Comas Iñaki, Coscollà Mireia, Gagneux Sebastien

Abstract excerpt

There is increasing evidence that strain variation in Mycobacterium tuberculosis complex (MTBC) might influence the outcome of tuberculosis infection and disease. To assess genotype-phenotype associations, phylogenetically robust molecular markers and appropriate genotyping tools are required. Most current genotyping methods for MTBC are based on mobile or repetitive DNA elements. Because these elements are prone...

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Identifiers

PMID: 22911768
DOI: 10.1371/journal.pone.0041253
PMCID: PMC3401130

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Source receipt: pubmed, retrieved 7 Sept 2026.

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