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Article

Robust barcoding and identification of Mycobacterium tuberculosis lineages for epidemiological and clinical studies.

Genome medicine - 14 Dec 2020

Napier Gary, Campino Susana, Merid Yared, Abebe Markos, Woldeamanuel Yimtubezinash, Aseffa Abraham, Hibberd Martin L, Phelan Jody, Clark Taane G

Abstract excerpt

BACKGROUND: Tuberculosis, caused by bacteria in the Mycobacterium tuberculosis complex (MTBC), is a major global public health burden. Strain-specific genomic diversity in the known lineages of MTBC is an important factor in pathogenesis that may affect virulence, transmissibility, host response and emergence of drug resistance. Fast and accurate tracking of MTBC strains is therefore crucial for infection...

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Identifiers

PMID: 33317631
DOI: 10.1186/s13073-020-00817-3
PMCID: PMC7734807

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Source receipt: pubmed, retrieved 7 Sept 2026.

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