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Article

Reduced genetic distance and high replication levels increase the RNA recombination rate of hepatitis delta virus.

Virus research - 2 Jan 2015

Lin Chia-Chi, Yang Zhi-Wei, Iang Shan-Bei, Chao Mei

Abstract excerpt

Hepatitis delta virus (HDV) replication is carried out by host RNA polymerases. Since homologous inter-genotypic RNA recombination is known to occur in HDV, possibly via a replication-dependent process, we hypothesized that the degree of sequence homology and the replication level should be related to the recombination frequency in cells co-expressing two HDV sequences. To confirm this, we separately...

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Share to Genetic Variation
Share to Hepatitis Delta Virus
Share to Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Recombination, Genetic

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RNA, Viral

Share to Transfection

Share to Virus Replication

Source

Identifiers

PMID: 25172581
DOI: 10.1016/j.virusres.2014.08.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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