Article
RNA recombination of hepatitis delta virus in natural mixed-genotype infection and transfected cultured cells.
Journal of virology - 1 Feb 2005
Wang Tzu-Chi, Chao Mei
Abstract excerpt
Most RNA viruses encode their own RNA polymerases for genome replication, and increasing numbers of them appear to be capable of undergoing RNA recombination. Here, we provide the first report of intergenotypic recombination in hepatitis delta virus (HDV), the only animal RNA virus that requires host RNA polymerase(s) for viral replication. In vivo, we analyzed RNA species derived from the serum of a patient with...
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