Article
RNA recombination in Hepatitis delta virus: Identification of a novel naturally occurring recombinant.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Dec 2017
Lin Chia-Chi, Lee Chi-Ching, Lin Siao-Han, Huang Po-Jung, Li Hsin-Pai, Chang Yu-Sun, Tang Petrus, Chao Mei
Abstract excerpt
BACKGROUND/PURPOSE: Hepatitis delta virus (HDV) is the only animal RNA virus that has an unbranched rod-like genome with ribozyme activity. It replicates in the nucleus by host RNA polymerase via a rolling circle mechanism. Similar to many RNA viruses encoding their own RNA-dependent RNA polymerases, homologous recombination of HDV occurs in mixed-genotype infections and in cultured cells cotransfected with two...
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