Article
Assembly of telomeric chromatin to create ALTernative endings.
Trends in cell biology - 1 Nov 2014
O'Sullivan Roderick J, Almouzni Genevieve
Abstract excerpt
Circumvention of the telomere length-dependent mechanisms that control the upper boundaries of cellular proliferation is necessary for the unlimited growth of cancer. Most cancer cells achieve cellular immortality by up-regulating the expression of telomerase to extend and maintain their telomere length. However, a small but significant number of cancers do so via the exchange of telomeric DNA between chromosomes...
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