Article
Predisposing role of vitamin D receptor (VDR) polymorphisms in the development of multiple sclerosis: A case-control study.
Journal of the neurological sciences - 15 Aug 2016
Abdollahzadeh Rasoul, Fard Mahsa Sobhani, Rahmani Farideh, Moloudi Kaveh, Kalani Behrooz Sadeghi, Azarnezhad Asaad
Abstract excerpt
Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS) with a complex etiology. Given the Vitamin D receptor (VDR) gene, it is considered an outstanding risk component associated with MS. The aim of the present study has been to explore and emphasize the role of ApaI, BsmI, TaqI and FokI polymorphisms of VDR gene in susceptibility to MS...
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