Article
Mitochondrial and nuclear genes as the cause of complex I deficiency.
Genetics and molecular research : GMR - 12 Sept 2013
Rezaee A R, Azadi A, Houshmand M, Mahmoodi F, Purpak Z, Safaei S, Karimi P, Ghabaee M, Sahraian M A
Abstract excerpt
Multiple sclerosis (MS) is an immunological inflammatory disease of the central nervous system. The pathogenesis of MS is incompletely understood, but various studies have suggested that mitochondrial dysfunction is associated with the disease. Mitochondria are among the main cellular sources of reactive oxygen and nitrogen species, and they play a pivotal role in many neuro-pathological conditions. The...
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