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Article

Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis.

The Journal of allergy and clinical immunology - 1 Sept 2014

Wu Yu-Chang B, James Louisa K, Vander Heiden Jason A, Uduman Mohamed, Durham Stephen R, Kleinstein Steven H, Kipling David, Gould Hannah J

Abstract excerpt

BACKGROUND: Previous studies of immunoglobulin gene sequences in patients with allergic diseases using low-throughput Sanger sequencing have limited the analytic depth for characterization of IgE repertoires. OBJECTIVES: We used a high-throughput, next-generation sequencing approach to characterize immunoglobulin heavy-chain gene (IGH) repertoires in patients with seasonal allergic rhinitis (AR) with the aim of...

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Source

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Identifiers

PMID: 25171866
DOI: 10.1016/j.jaci.2014.07.010
PMCID: PMC4151999

Genes

IGH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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