Article
Diversity of immunoglobulin E-encoding transcripts in sinus mucosa of subjects diagnosed with non-allergic fungal eosinophilic sinusitis.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jun 2011
Levin M, Tan L W, Baker L, Wormald P-J, Greiff L, Ohlin M
Abstract excerpt
BACKGROUND: The role of allergy in the aetiopathogenesis of chronic rhinosinusitis (CRS) remains controversial. For example, in some cases with sinus fungal infections allergy can be demonstrated by standard tests. In other cases, such signs can be absent despite elevated levels of IgE-positive cells in sinus tissue and the presence of IgE and eosinophils in the sinus mucous. OBJECTIVE: To define the nature of...
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