Article
Senescence-associated secretory phenotype and its possible role in chronic obstructive pulmonary disease.
American journal of respiratory cell and molecular biology - 1 Sept 2014
Kumar Manish, Seeger Werner, Voswinckel Robert
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is a major disease of the lungs. It primarily occurs after a prolonged period of cigarette smoking. Chronic inflammation of airways and the alveolar space as well as lung tissue destruction are the hallmarks of COPD. Recently it has been shown that cellular senescence might play a role in the pathogenesis of COPD. Cellular senescence comprises signal transduction...
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