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Senescence: Pathogenic Driver in Chronic Obstructive Pulmonary Disease

17 Jun 2022

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is recognized as a disease of accelerated lung aging. Over the past two decades, mounting evidence suggests an accumulation of senescent cells within the lungs of patients with COPD that contributes to dysregulated tissue repair and the secretion of multiple inflammatory proteins, termed the senescence-associated secretory phenotype (SASP). Cellular senescence in COPD...

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PMID: 35744080
DOI: 10.3390/medicina58060817

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