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Cellular Senescence in the Lung: The Central Role of Senescent Epithelial Cells

6 May 2020

Abstract excerpt

Cellular senescence is a key process in physiological dysfunction developing upon aging or following diverse stressors including ionizing radiation. It describes the state of a permanent cell cycle arrest, in which proliferating cells become resistant to growth-stimulating factors. Senescent cells differ from quiescent cells, which can re-enter the cell cycle and from finally differentiated cells: morphological...

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PMID: 32384619
DOI: 10.3390/ijms21093279

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