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Potential Role of Cellular Senescence in Asthma

11 Feb 2020

Abstract excerpt

Cellular senescence is a complicated process featured by irreversible cell cycle arrest and senescence-associated secreted phenotype (SASP), resulting in accumulation of senescent cells, and low-grade inflammation. Cellular senescence not only occurs during the natural aging of normal cells, but also can be accelerated by various pathological factors. Cumulative studies have shown the role of cellular senescence...

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PMID: 32117985
DOI: 10.3389/fcell.2020.00059

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