Article
UGT1A1*28 is associated with greater decrease in serum K⁺ levels following oral intake of procaterol.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Apr 2015
Yokoe Norihito, Yamaguchi Etsuro, Nishimura Masaki, Tanaka Hiroyuki, Takahashi Ayumu, Baba Kenji, Gosho Masahiko, Okada Shoshiro
Abstract excerpt
BACKGROUND AND OBJECTIVE: Procaterol is a potent β2-agonist frequently used for the management of asthma and chronic obstructive pulmonary disease. The efficacy and adverse effects of β2-agonists are heterogeneous in individual patients, which may be partly caused by genetic variations in metabolizing enzymes and receptor molecules. The present study was designed to analyze the relationship between gene...
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