Article
Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites.
Genes & development - 1 Apr 2006
Parrish Jay Z, Kim Michael D, Jan Lily Yeh, Jan Yuh Nung
Abstract excerpt
Dendrite arborization patterns are critical determinants of neuronal function. To explore the basis of transcriptional regulation in dendrite pattern formation, we used RNA interference (RNAi) to screen 730 transcriptional regulators and identified 78 genes involved in patterning the stereotyped dendritic arbors of class I da neurons in Drosophila. Most of these transcriptional regulators affect dendrite...
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