Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells.

Nature communications - 27 Feb 2020

McNeill Elizabeth M, Warinner Chloe, Alkins Stephen, Taylor Alicia, Heggeness Hansine, DeLuca Todd F, Fulga Tudor A, Wall Dennis P, Griffith Leslie C, Van Vactor David

Abstract excerpt

Micro(mi)RNA-based post-transcriptional regulatory mechanisms have been broadly implicated in the assembly and modulation of synaptic connections required to shape neural circuits, however, relatively few specific miRNAs have been identified that control synapse formation. Using a conditional transgenic toolkit for competitive inhibition of miRNA function in Drosophila, we performed an unbiased screen for novel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Calmodulin-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Adhesion Molecules, Neuronal

Share to MicroRNAs

Share to Morphogenesis

Share to Neuromuscular Junction

Share to Presynaptic Terminals

Source

Open in PubMed Open full text

Identifiers

PMID: 32107390
DOI: 10.1038/s41467-020-14761-8
PMCID: PMC7046720

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells.PMID 32107390Read ↗

Neurophysiological defects and neuronal gene deregulation in Drosophila mir-124 mutants.Semantic proximity Read ↗

UNC-30/PITX coordinates neurotransmitter identity with postsynaptic GABA receptor clusteringSemantic proximity Read ↗

miR-8 controls synapse structure by repression of the actin regulator enabled.Semantic proximity Read ↗

Unraveling the mechanisms of synapse formation and axon regeneration: the awesome power of C. elegans genetics.Semantic proximity Read ↗

Genome-wide P-element screen for Drosophila synaptogenesis mutants.Semantic proximity Read ↗

Neuromuscular synaptogenesis in wild-type and mutant zebrafish.Semantic proximity Read ↗

Synaptogenesis.Semantic proximity Read ↗

RSY-1 is a local inhibitor of presynaptic assembly in C. elegans.Semantic proximity Read ↗

rpm-1, a conserved neuronal gene that regulates targeting and synaptogenesis in C. elegans.Semantic proximity Read ↗

Systematic analysis of genes required for synapse structure and function.Semantic proximity Read ↗

Glia-derived exosomal miR-274 targets Sprouty in trachea and synaptic boutons to modulate growth and responses to hypoxia.Semantic proximity Read ↗

Developmental arrest of Drosophila larvae elicits presynaptic depression and enables prolonged studies of neurodegeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.