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Article

Genetic and polygenic investigation of heart rate variability to identify biomarkers associated with Anxiety disorders.

Psychiatry research - 1 Aug 2024

Tomasi Julia, Lisoway Amanda J, Zai Clement C, Zai Gwyneth, Richter Margaret A, Sanches Marcos, Herbert Deanna, Mohiuddin Ayeshah G, Tiwari Arun K, Kennedy James L

Abstract excerpt

Given that anxiety disorders (AD) are associated with reduced vagally-mediated heart rate variability (HRV), genetic variants related to HRV may provide insight into anxiety etiology. This study used polygenic risk scores (PRS) to explore the genetic overlap between AD and HRV, and investigated whether HRV-related polymorphisms influence anxiety risk. Resting vagally-mediated HRV was measured using a wearable...

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Source

Identifiers

PMID: 38850888
DOI: 10.1016/j.psychres.2024.115982

Genes

GNG11
NDUFA11
HCN4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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