Article
Genetics of gene expression characterizes response to selective breeding for alcohol preference.
Genes, brain, and behavior - 1 Nov 2014
Hoffman P L, Saba L M, Flink S, Grahame N J, Kechris K, Tabakoff B
Abstract excerpt
Numerous selective breeding experiments have been performed with rodents, in an attempt to understand the genetic basis for innate differences in preference for alcohol consumption. Quantitative trait locus (QTL) analysis has been used to determine regions of the genome that are associated with the behavioral difference in alcohol preference/consumption. Recent work suggests that differences in gene expression...
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