Article
Gene expression in animals with different acute responses to ethanol.
Addiction biology - 1 Mar 2005
Hoffman Paula, Tabakoff Boris
Abstract excerpt
The genetic and environmental contributions to differences in response to ethanol have been examined widely using inbred strains, selected lines and genetically engineered (transgenic and 'knock-out') animals. In addition, recombinant inbred strains have been used to identify QTLs (chromosomal regions) associated with particular responses to ethanol. If the polymorphism that underlies such a QTL is localized...
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