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Article

Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice.

Journal of neuroinflammation - 27 Aug 2014

François Arnaud, Rioux Bilan Agnès, Quellard Nathalie, Fernandez Béatrice, Janet Thierry, Chassaing Damien, Paccalin Marc, Terro Faraj, Page Guylène

Abstract excerpt

BACKGROUND: In recent years, studies have sought to understand the mechanisms involved in the alteration of autophagic flux in Alzheimer's disease (AD). Alongside the recent description of the impairment of lysosomal acidification, we wanted to study the relationships between inflammation and autophagy, two physiological components deregulated in AD. Therefore, a longitudinal study was performed in APPswePS1dE9...

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Identifiers

PMID: 25158693
DOI: 10.1186/s12974-014-0139-x
PMCID: PMC4154524

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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