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Article

Polymorphisms of Arsenic (+3 Oxidation State) Methyltransferase and Arsenic Methylation Capacity Affect the Risk of Bladder Cancer.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Jul 2018

Lin Ying-Chin, Chen Wei-Jen, Huang Chao-Yuan, Shiue Horng-Sheng, Su Chien-Tien, Ao Pui-Lam, Pu Yeong-Shiau, Hsueh Yu-Mei

Abstract excerpt

The mechanisms underlying how arsenic methylation capacity affects bladder cancer (BC) are still unclear. The objective of this study was to explore the effects of polymorphisms of arsenic (+3 oxidation state) methyltransferase (AS3MT) on BC risk. We conducted a hospital-based study and enrolled 216 BC and 648 healthy controls from 2007 to 2011. Urinary arsenic profiles were measured using high-performance liquid...

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PMID: 29669044
DOI: 10.1093/toxsci/kfy087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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