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Article

Transcriptome‐Wide Analysis of Messenger RNA Decay in Normal and Osteoarthritic Human Articular Chondrocytes

22 Aug 2014

Abstract excerpt

OBJECTIVE: Messenger RNA (mRNA) decay rates control not only gene expression levels, but also responsiveness to altered transcriptional input. We undertook this study to examine transcriptome-wide posttranscriptional regulation in both normal and osteoarthritic (OA) human articular chondrocytes. METHODS: Human articular chondrocytes were isolated from normal or OA tissue. Equine articular chondrocytes were...

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PMID: 25155964
DOI: 10.1002/art.38849

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