Article

Transcriptomic changes during the replicative senescence of human articular chondrocytes

2024-10-02

Abstract excerpt

<title>Abstract</title> <p>Objective Aging is a major risk factor for OA, but the specific mechanisms underlying this connection remain unclear. Although chondrocytes rarely divide in adult articular cartilage, they undergo replicative senescence <italic>in vitro</italic> which provides an opportunity to study changes related to aging under controlled laboratory conditions. Methods Cartilage was recovered from...

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Literature Corpus work: d29533e2-ffc9-55a6-83a7-0ea85ee442d9
DOI: 10.21203/rs.3.rs-4876006/v1

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