Article
Characterising the effect of age and sex on post-transcriptional regulation in synovial joint tissues
2025-09-20
Abstract excerpt
Age and sex are major risk factors for joint degeneration and disease susceptibility. While epigenetic and post-transcriptional mechanisms are known to be influenced by these factors, their effects on mRNA kinetics and configuration in musculoskeletal tissues remain poorly defined. To address this gap, we used an equine model to examine how age and sex impact mRNA stability in joint tissues. We measured global tra...
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Identifiers and source
- Literature Corpus work
- 607d5de6-16ae-511d-b95f-52eda76edd2e
- DOI
- 10.1101/2025.09.18.677035