Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Discoidin domain receptor 1 is a novel transcriptional target of ZEB 1 in breast epithelial cells undergoing H ‐ R as‐induced epithelial to mesenchymal transition

23 Aug 2014

Abstract excerpt

The epithelial-to-mesenchymal transition (EMT) process allows carcinoma cells to dissociate from the primary tumor thereby facilitating tumor cell invasion and metastasis. Ras-dependent hyperactive signaling is commonly associated with tumorigenesis, invasion, EMT, and metastasis. However, the downstream effectors by which Ras regulates EMT remain ill defined. In this study, we show that the H-Ras pathway leads...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cell Adhesion Molecules Research
Share to Medicinal Plant Pharmacodynamics Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25155634
DOI: 10.1002/ijc.29154

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Discoidin domain receptor 1 is a novel transcriptional target of ZEB 1 in breast epithelial cells undergoing H ‐ R as‐induced epithelial to mesenchymal transitionPMID 25155634Read ↗

Epithelial–Mesenchymal Transition and Tumor Suppression Are Controlled by a Reciprocal Feedback Loop between ZEB1 and Grainyhead-like-2Semantic proximity Read ↗

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer.Semantic proximity Read ↗

ZEB2 Regulates Endocrine Therapy Sensitivity and Metastasis in Luminal A Breast Cancer Through a Non-Canonical MechanismSemantic proximity Read ↗

Genome–wide binding of transcription factor ZEB1 in triple‐negative breast cancer cellsSemantic proximity Read ↗

ETS1 is coexpressed with ZEB2 and mediates ZEB2‐induced epithelial‐mesenchymal transition in human tumorsSemantic proximity Read ↗

ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy ResistanceSemantic proximity Read ↗

Induction of ZEB Proteins by Inactivation of RB Protein Is Key Determinant of Mesenchymal Phenotype of Breast CancerSemantic proximity Read ↗

The GRHL2/ZEB Feedback Loop-A Key Axis in the Regulation of EMT in Breast CancerSemantic proximity Read ↗

Identification of a PEAK1/ZEB1 signaling axis during TGFβ/fibronectin-induced EMT in breast cancerSemantic proximity Read ↗

Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cellsSemantic proximity Read ↗

Long non‐coding RNA ZEB2‐AS1 promotes the proliferation, metastasis and epithelial mesenchymal transition in triple‐negative breast cancer by epigenetically activating ZEB2Semantic proximity Read ↗

Regulation of ZEB1 Function and Molecular Associations in Tumor Progression and MetastasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.