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Article

MicroRNA-101 targets EZH2, MCL-1 and FOS to suppress proliferation, invasion and stem cell-like phenotype of aggressive endometrial cancer cells.

Oncotarget - 15 Aug 2014

Konno Yosuke, Dong Peixin, Xiong Ying, Suzuki Fumihiko, Lu Jiabin, Cai Muyan, Watari Hidemichi, Mitamura Takashi, Hosaka Masayoshi, Hanley Sharon J B, Kudo Masataka, Sakuragi Noriaki

Abstract excerpt

MicroRNA-101 has been implicated as a tumor suppressor miRNA in human tumors. However, its potential functional impact and the underlying mechanisms in endometrial cancer progression have not been determined. Here, we report that in aggressive endometrial cancer cells, re-expression of microRNA-101 leads to inhibition of cell proliferation and induction of apoptosis and senescence. Ectopic overexpression of...

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Identifiers

PMID: 25153722
DOI: 10.18632/oncotarget.2157
PMCID: PMC4171612

Genes

FOS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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