Article
MicroRNA-99a inhibits tumor aggressive phenotypes through regulating HOXA1 in breast cancer cells.
Oncotarget - 20 Oct 2015
Wang Xiaolong, Li Yaming, Qi Wenwen, Zhang Ning, Sun Mingjuan, Huo Qiang, Cai Chang, Lv Shangge, Yang Qifeng
Abstract excerpt
MicroRNAs (miRNAs) are key regulators of tumor progression. Based on microarray data, we identified miR-99a as a potential tumor suppressor in breast cancer. Expression of miR-99a is frequently down-regulated in breast cancer tissues relative to normal breast tissues. Reduced miR-99a expression was highly associated with lymph node metastasis and shorter overall survival of patients with breast cancer. Gain- and...
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