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Article

50-bp Ins/Del polymorphism of SOD1 is associated with increased risk of cardiovascular disease.

Acta medica Iranica - 1 Jan 2014

Eskandari-Nasab Ebrahim, Kharazi-Nejad Eslam, Nakhaee Alireza, Afzali Masoumeh, Tabatabaei Seyed Payman, Tirgar-Fakheri Kourosh, Hashemi Mohammad

Abstract excerpt

Compelling evidence suggests that the oxidative stress plays a key role in the pathophysiology of cardiovascular disease (CVD). Superoxide dismutase (SOD) enzymes play a major role in detoxification of reactive oxygen species and protection against oxidative stress. We examined the possible association between a 50-bp insertion/deletion in the SOD1 promoter 1684-bp upstream of the SOD1 ATG with CVD in an Iranian...

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Identifiers

PMID: 25149881

Genes

SOD1
INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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