Article
50 bp deletion in promoter superoxide dismutase 1 gene and increasing risk of cardiovascular disease in Mashhad stroke and heart atherosclerotic disorder cohort study.
BioFactors (Oxford, England) - 1 Jan 2020
Darroudi Susan, Tajbakhsh Amir, Esmaily Habibollah, Ghazizadeh Hamideh, Zamani Parvin, Sadabadi Fatemeh, Tayefi Maryam, Tayefi Batool, Fereydouni Narges, Mouhebati Mohsen, Akbari Sark Noushin, Avan Amir, Ferns Gordon A, Mohammadpour Amir H, Asadi Zahra, Ghayour-Mobarhan Majid
Abstract excerpt
Cardiovascular disease (CVD), one of the main mortality causes worldwide is considered to be affected by general oxidative stress and inadequacy antioxidant system. Superoxide dismutase 1 (SOD1), a cytosolic antioxidant enzyme has a key role in neutralizing the excessive prooxidant by scavenging the super oxide anions. SOD1 polymorphic variants exhibit the altered activity properties. In the current study, we are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.