Article
MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis.
Cancer gene therapy - 1 Nov 2020
Karimzadeh Mohammad Reza, Zarin Maryam, Ehtesham Naeim, Khosravi Sharifeh, Soosanabadi Mohsen, Mosallaei Meysam, Pourdavoud Peyman
Abstract excerpt
Inflammation, among environmental risk factors, is one of the most important contributors to colorectal cancer (CRC) development. In this way, studies revealed that the incidence of CRC in inflammatory bowel disease patients is up to 60% higher than the general population. MicroRNAs (miRNAs), small noncoding RNA molecules, have attracted excessive attention due to their fundamental role in various aspects of...
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