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Article

NR0B2 Is a Key Factor for Gastric Diseases: A GEO Database Analysis Combined with Drug-Target Mendelian Randomization.

Genes - 16 Sept 2024

Li Zhengwen, Xu Lijia, Huang Dongliang, Li Chujie, Haenen Guido R M M, Zhang Ming

Abstract excerpt

Small Heterodimer Partner (SHP; NR0B2) is an orphan receptor that acts as a transcriptional regulator, controlling various metabolic processes, and is a potential therapeutic target for cancer. Examining the correlation between the expression of NR0B2 and the risk of gastric diseases could open a new path for treatment and drug development. The Gene Expression Omnibus (GEO) database was utilized to explore NR0B2...

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Identifiers

PMID: 39336801
DOI: 10.3390/genes15091210
PMCID: PMC11431353

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