PTGS2 (COX2) -765G>C gene polymorphism and risk of sporadic colorectal cancer in Iranian population.

doi:10.1007/s11033-011-1319-8

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Article

PTGS2 (COX2) -765G>C gene polymorphism and risk of sporadic colorectal cancer in Iranian population.

Molecular biology reports - 1 May 2012

Daraei Abdolreza, Salehi Rasoul, Mohamadhashem Faezeh

Abstract excerpt

Colorectal cancer (CRC) is one of the leading cancers worldwide. Through genome wide association studies, several single nucleotide polymorphisms scattered in the genome emerged to be influential in the development of sporadic CRC in some populations. However, replicative studies failed to prove a particular SNP-CRC association in populations and ethnic groups. Cyclooxygenase-2 (PTGS2) is a crucial enzyme...

Topics

Base Sequence
Case-Control Studies
Colorectal Neoplasms
Cyclooxygenase 2
DNA Mutational Analysis
Demography
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Iran
Molecular Sequence Data
Polymorphism, Single Nucleotide
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 22173719
DOI: 10.1007/s11033-011-1319-8

Genes

PTGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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