Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reassessment of genotype 1 hepatitis C virus subtype misclassification by LiPA 2.0: implications for direct-acting antiviral treatment.

Journal of clinical microbiology - 1 Nov 2014

Guelfo Javier R, Macias Juan, Neukam Karin, Di Lello Federico A, Mira Jose A, Merchante Nicolas, Mancebo María, Nuñez-Torres Rocío, Pineda Juan A, Real Luis M

Abstract excerpt

The accuracy of LiPA 2.0 for hepatitis C virus 1 (HCV-1) subtype classification was analyzed. LiPA 2.0 genotype results from 101 HCV-1-infected patients were compared to genotype findings determined by direct core sequencing. Eleven (11%) samples were misclassified. Given the influence of the HCV-1-subtype in the anti-HCV therapy response, an alternative classification method is warranted.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C, Chronic

Share to Molecular Sequence Data

Share to RNA, Viral

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 25143567
DOI: 10.1128/JCM.02209-14
PMCID: PMC4313243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reassessment of genotype 1 hepatitis C virus subtype misclassification by LiPA 2.0: implications for direct-acting antiviral treatment.PMID 25143567Read ↗

NS3 genomic sequencing and phylogenetic analysis as alternative to a commercially available assay to reliably determine hepatitis C virus subtypes 1a and 1b.Semantic proximity Read ↗

Comparison of three different HCV genotyping methods: core, NS5B sequence analysis and line probe assay.Semantic proximity Read ↗

Evaluation of Versant hepatitis C virus genotype assay (LiPA) 2.0.Semantic proximity Read ↗

Comparison of cobas HCV GT against Versant HCV Genotype 2.0 (LiPA) with confirmation by Sanger sequencing.Semantic proximity Read ↗

Hepatitis C virus (HCV) genotype 1 subtype identification in new HCV drug development and future clinical practice.Semantic proximity Read ↗

Hepatitis C virus deep sequencing for sub-genotype identification in mixed infections: A real-life experience.Semantic proximity Read ↗

Evaluation of sequencing of HCV core/E1, NS5A and NS5B as a genotype predictive tool in comparison with commercial assays targeting 5'UTR.Semantic proximity Read ↗

Validation of the INNO-LiPA HBV DR assay (version 2) in monitoring hepatitis B virus-infected patients receiving nucleoside analog treatment.Semantic proximity Read ↗

Evaluation of a new-generation line-probe assay that detects 5' untranslated and core regions to genotype and subtype hepatitis C virus.Semantic proximity Read ↗

Improvement of hepatitis C virus (HCV) genotype determination with the new version of the INNO-LiPA HCV assay.Semantic proximity Read ↗

Determination of the hepatitis C virus subtype: comparison of sequencing and reverse hybridization assays.Semantic proximity Read ↗

The need for a sequencing-based assay to supplement the Abbott m2000 RealTime HCV Genotype II assay: a 1 year analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.