Article
Evaluation of sequencing of HCV core/E1, NS5A and NS5B as a genotype predictive tool in comparison with commercial assays targeting 5'UTR.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2015
McCormick Adele L, Macartney Malcolm J, Abdi-Abshir Ikran, Labbett Wendy, Smith Colette, Irish Dianne, Webster Daniel P, Haque Tanzina
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) genotyping is required for tailoring the dose and duration of antiviral therapy, predicting virological response rates, and selecting future treatment options. OBJECTIVE: To establish whether baseline genotypes, performed by INNO-LiPA Version 1.0 (v1.0), before 2008, were valid for making treatment decisions now or whether genotypic determination should be repeated....
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