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Article

The need for a sequencing-based assay to supplement the Abbott m2000 RealTime HCV Genotype II assay: a 1 year analysis.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jul 2014

Benedet Marlin, Adachi Dena, Wong Anita, Wong Sallene, Pabbaraju Kanti, Tellier Raymond, Tang Julian W

Abstract excerpt

BACKGROUND: Hepatitis C (HCV) genotyping is important for treatment planning. The Abbott m2000 RealTime HCV Genotype II assay is a PCR-based assay targeting specific regions of the 5'NCR gene for genotypes 1-6, and the NS5b gene for subgenotypes 1a/1b. However, not all genotypes can be resolved, with results being reported as: 'indeterminate', 'mixed', 'genotype X reactivity with Y', or just the major genotype 1...

Topics

Genotype
Hepacivirus
Hepatitis C
Humans
Phylogeny
RNA, Viral
Reagent Kits, Diagnostic
Sequence Analysis, DNA
Viral Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24794397
DOI: 10.1016/j.jcv.2014.04.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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