Article
A metabolic trade-off between phosphate and glucose utilization in Escherichia coli.
Molecular bioSystems - 1 Nov 2014
Behrends Volker, Maharjan Ram P, Ryall Ben, Feng Lu, Liu Bin, Wang Lei, Bundy Jacob G, Ferenci Thomas
Abstract excerpt
Getting the most out of available nutrients is a key challenge that all organisms face. Little is known about how they optimize and balance the simultaneous utilization of multiple elemental resources. We investigated the effects of long-term phosphate limitation on carbon metabolism of the model organism Escherichia coli using chemostat cultures. We profiled metabolic changes in the growth medium over time and...
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