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Article

Synergistic interactions between glycogen and trehalose mediate adaptation to the stationary phase in E. coli.

Journal of bacteriology - 21 May 2026

Jakowec Nicolaus A, Chopra Manat, Finegan Melissa, Finkel Steven E

Abstract excerpt

Glycogen and trehalose are multifunctional carbohydrates that contribute to bacterial adaptability, stress tolerance, and energy homeostasis, yet the mechanisms underlying these characteristics are not fully elucidated. In Escherichia coli, we reveal a metabolic and regulatory coupling between glycogen and trehalose with the global flux-sensing regulators cAMP-CRP and Cra during the stationary phase. Using...

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Identifiers

PMID: 42017685
DOI: 10.1128/jb.00544-25
PMCID: PMC13192265

Genes

CRP
PTS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

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