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Article

Gene Dispensability in Escherichia coli Grown in Thirty Different Carbon Environments.

mBio - 29 Sept 2020

Tong Madeline, French Shawn, El Zahed Sara S, Ong Wai Kit, Karp Peter D, Brown Eric D

Abstract excerpt

Central metabolism is a topic that has been studied for decades, and yet, this process is still not fully understood in Escherichia coli, perhaps the most amenable and well-studied model organism in biology. To further our understanding, we used a high-throughput method to measure the growth kinetics of each of 3,796 E. coli single-gene deletion mutants in 30 different carbon sources. In total, there were 342...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32994326
DOI: 10.1128/mBio.02259-20
PMCID: PMC7527729

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