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Article

HIV multi-drug resistance at first-line antiretroviral failure and subsequent virological response in Asia.

Journal of the International AIDS Society - 1 Jan 2014

Jiamsakul Awachana, Sungkanuparph Somnuek, Law Matthew, Kantor Rami, Praparattanapan Jutarat, Li Patrick C K, Phanuphak Praphan, Merati Tuti, Ratanasuwan Winai, Lee Christopher K C, Ditangco Rossana, Mustafa Mahiran, Singtoroj Thida, Kiertiburanakul Sasisopin

Abstract excerpt

INTRODUCTION: First-line antiretroviral therapy (ART) failure often results from the development of resistance-associated mutations (RAMs). Three patterns, including thymidine analogue mutations (TAMs), 69 Insertion (69Ins) and the Q151M complex, are associated with resistance to multiple-nucleoside reverse transcriptase inhibitors (NRTIs) and may compromise treatment options for second-line ART. METHODS: We...

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Identifiers

PMID: 25141905
DOI: 10.7448/IAS.17.1.19053
PMCID: PMC4139921

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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